A Study to Investigate the Clinical Outcome and Quality of Life in Chinese Post-operative CRSwNP Patients

Recruiting now

Conditions studied: Chronic Rhinosinusitis With Nasal Polyps

In brief

This is a prospective, multicenter real-world study to describe the postoperative outcomes and quality of life, disease control and characteristics of patients who underwent surgery, as well as economic burden and post-operative treatment patterns in Chinese patients with CRSwNP recurrence.

Key facts

Study ID

NCT07446738

Run by

AstraZeneca

People needed

200

Starts

2026-03-19

Expected to finish

2027-10-21

Last updated by the study team

2026-07-08

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participant must be 16 years of age or older, at the time of signing the informed consent.
• Participants with a documented diagnosis of CRSwNP.
• Endoscopic nasal polypectomy is performed during the screening period.
• Voluntarily participate and sign the informed consent form as described in A 3.
• No history or current psychiatric disorders, with normal cognitive functions including understanding, expression, and orientation.

You may not qualify if…

• Any significant disease or disorder that the investigator believes may place the patient at risk or may affect the study results or the patient's ability to participate in the study.
• Currently participating in an interventional study.
• Patients who are unable to independently complete questionnaires due to language barriers or mental status.

Where it is running

• Research Site — Xiamen, China (enrolling)
• Research Site — Wuhan, China (enrolling)
• Research Site — Changchun, China (enrolling)
• Research Site — Chengdu, China (enrolling)
• Research Site — Guangzhou, China (enrolling)
• Research Site — Guangzhou, China (enrolling)
• Research Site — Guangzhou, China (enrolling)
• Research Site — Haikou, China (enrolling)
• Research Site — Kunming, China (enrolling)
• Research Site — Nanchang, China (enrolling)
• Research Site — Nanjing, China (enrolling)
• Research Site — Nanning, China (enrolling)
• Research Site — Shanghai, China (enrolling)
• Research Site — Shenzhen, China (enrolling)
• Research Site — Ürümqi, China (enrolling)
• Research Site — Wuhan, China (enrolling)
• Research Site — Changsha, China
• Research Site — Qingdao, China

Full record on ClinicalTrials.gov

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