Catheter Ablation of Advanced Forms of Atrial Fibrillation

Enrolling by invitation · Not applicable

Conditions studied: Persistent Atrial Fibrillation, Persistent Atrial Fibrillation Longstanding

In brief

The purpose of this study is to evaluate feasibility, safety, and efficacy of pulmonary vein isolation combined with posterior left atrial isolation and multiple linear lesions in both atria in patients with persistent and long-standing persistent atrial fibrillation.

Key facts

Study ID

NCT07446244

Run by

University Medical Centre Ljubljana

People needed

50

Starts

2026-03-25

Expected to finish

2028-03-01

Last updated by the study team

2026-04-06

Who can join

Age: any, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• persistent atrial fibrillation or long-standing persistent atrial fibrillation
• severely enlarged left atrium (LAVI above 50 ml/m2)

You may not qualify if…

• contraindications for electroporation
• contraindications for general anaesthesia
• age above 80 years
• less than 1 year life expectancy
• thrombus formation in left atrium
• acute life-threatening disease
• severe valvular disease requiring intervention
• previous ablation in left atrium
• secondary atrial fibrillation

Where it is running

• University Medical Centre Ljubljana — Ljubljana, Osrednjaslovenska, Slovenia

Full record on ClinicalTrials.gov

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