Transdiscal vs Paravertebral Neurolytic Splanchnic Nerve Block for Upper Abdominal Cancer Pain

Recruiting now · Not applicable

Conditions studied: Cancer Pain

In brief

This study aims to compare the efficacy of fluoroscopy-guided paravertebral (PV) and transdiscal (TD) approaches for splanchnic nerve neurolysis in patients with upper abdominal cancer-related pain (e.g., gastric, pancreatic, and hepatic malignancies). Treatment response will be assessed using the Numerical Rating Scale (NRS), and the impact of both techniques on quality of life will be evaluated with the EORTC QLQ-C30 questionnaire.

Key facts

Study ID

NCT07445386

Run by

Ankara Etlik City Hospital

People needed

56

Starts

2026-02-16

Expected to finish

2026-09-16

Last updated by the study team

2026-03-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Severe abdominal pain (NRS > 6) due to upper intra-abdominal organ malignancies (such as gastric, pancreatic, or hepatic cancer).
• Failure of pain control with conservative treatment modalities.

You may not qualify if…

• Presence of local anatomical variations
• Localized or systemic infection involving the procedural site
• Pregnancy
• Coagulopathy
• Presence of unstable psychiatric disorders

Where it is running

• Ankara Etlik City Hospital — Ankara, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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