Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia
Recruiting now · Not applicable
Conditions studied: Laryngeal Dystonia
In brief
Laryngeal dystonia (LD) is a focal dystonia affecting laryngeal muscles, causing involuntary spasms that impair speech production. Recent research demonstrated that non-invasive vibrotactile stimulation (VTS) of the laryngeal area can provide acute symptom relief in up to 57% of patients, with improvements in voice quality and reductions in perceived speech effort lasting from minutes to several days. However, the neural mechanisms underlying this therapeutic effect and the factors determining individual treatment response remain incompletely understood. The objective is to evaluate the acute effects of VTS on voice and speech parameters in participants with LD while characterizing associated changes in brain resting-state networks using magnetic resonance imaging (MRI).
Key facts
- Study ID
- NCT07443891
- Run by
- University of Minnesota
- People needed
- 20
- Starts
- 2026-01-14
- Expected to finish
- 2027-02-28
- Last updated by the study team
- 2026-03-19
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.
Where it is running
- University of Minnesota — Minneapolis, Minnesota, United States (enrolling)
Full record on ClinicalTrials.gov
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