Incidence of Postoperative Diaphragmatic Dysfunction in Pregnant Women With Preeclampsia
Recruiting now
Conditions studied: Preecalmpsia
In brief
Preeclampsia with severe features remains a leading contributor to maternal morbidity and mortality, particularly in low- and middle-income countries. It is defined by hypertension and involvement of multiple organ systems, including renal, hepatic, hematologic, and neurologic pathways. The interplay of endothelial dysfunction, capillary leakage, and disrupted fluid balance in these patients increases their susceptibility to perioperative pulmonary complications. Although respiratory complications in preeclampsia are clinically significant, the true incidence of postoperative diaphragmatic dysfunction in women with severe disease is not well established. Existing literature largely emphasizes general respiratory failure, pulmonary edema, or the need for mechanical ventilation, rather than specifically evaluating diaphragmatic performance with objective methods such as ultrasound. The current study sought to determine the incidence and identify risk factors for postoperative diaphragmatic dysfunction in women with severe preeclampsia following cesarean delivery.
Key facts
- Study ID
- NCT07443345
- Run by
- Cairo University
- People needed
- 52
- Starts
- 2026-03-09
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2026-03-11
Who can join
Age: 20 and older, up to 40. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Patients with severe preeclampsia undergoing cesarean section
- Gestational age > 32 weeks
You may not qualify if…
- • Age < 20 years.
- Diabetic
- Patients with neuromuscular diseases.
- Patient refusal.
- Contraindications to magnesium sulphate administration
- Inability to obtain adequate ultrasound views
Where it is running
- Cairo University Hospitals — Cairo, Egypt (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.