Auricular Vagus Nerve Stimulation Combined With Rehabilitation in Parkinson's Disease
Enrolling by invitation · Not applicable · Has a placebo group
Conditions studied: PARKINSON DISEASE (Disorder)
In brief
Parkinson's disease (PD) is a progressive, neurodegenerative movement disorder characterized by a combination of motor and non-motor symptoms. Auricular vagus nerve stimulation (aVNS), one of the physiotherapy methods used in PD, has been shown in studies to have a positive effect on symptoms such as motor symptoms, gait disturbance, freezing, and cognitive impairment, and is considered a safe and feasible method. The aim of this study is to investigate the effects of neurological physiotherapy and rehabilitation, in combination with aVNS application, on balance, gait, and clinical symptoms in individuals with PD.
Key facts
- Study ID
- NCT07440563
- Run by
- Gazi University
- People needed
- 20
- Starts
- 2026-03-03
- Expected to finish
- 2027-04-23
- Last updated by the study team
- 2026-03-05
Who can join
Age: 40 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosis of Parkinson's disease confirmed by a neurologist according to the United Kingdom Brain Bank criteria
- Age 40 years or older
- Hoehn and Yahr stage between 1 and 3 according to the Modified Hoehn and Yahr Staging Scale
- Stable pharmacological treatment regimen
- Ability to turn 180 degrees and walk 30 meters independently without assistance
You may not qualify if…
- Score below 21 on the Montreal Cognitive Assessment (MoCA)
- Presence of uncorrected visual or hearing impairments
- Presence of additional neurological (e.g., migraine), orthopedic (e.g., osteoarthritis), or cardiovascular conditions (e.g., myocardial infarction, uncontrolled hypertension, arrhythmias)
- Presence of a cardiac pacemaker
- Presence of metallic implants in the head or neck region
- History of deep brain stimulation surgery
Where it is running
- Gazi University — Ankara, Please Select, Turkey (Türkiye)
Full record on ClinicalTrials.gov
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