Older Age and Generalization

Recruiting now · Not applicable

Conditions studied: Aging

In brief

The goal of this clinical is to learn how the brain supports different kinds of memory decisions in healthy young and older adults. The main question it seeks to answer is: Do older adults make memory decisions by integrating across experiences? Young (aged 18-30 years) and older (aged 65-80 years) participants will complete a memory task while undergoing functional MRI to measure their brain responses. Researchers will compare brain measures of integration in older adults to those of young adults to see if integration increases in older age.

Key facts

Study ID

NCT07440017

Run by

Caitlin Bowman

People needed

360

Starts

2026-06-15

Expected to finish

2029-12-31

Last updated by the study team

2026-06-17

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Either aged 18-30 years (young adults) or aged 65-80 years (older adults) (self-report)
• Fluent in English (self-report)
• Right-handed (self-report)
• Cognitively healthy (self report verified by score > 24 on Montreal Cognitive Assessment)
• Self-reported normal or corrected-to-normal vision

You may not qualify if…

• Self-reported neurological disorder (e.g., Alzheimer's or Parkinson's disease)
• Self-reported uncontrolled hypertension, diabetes, or thyroid disorder
• Having conditions or devices that are unsafe for MRI (assessed via imaging center's MRI safety screening form)
• Self-reported difficulty lying still on one's back for 1-2 hours

Where it is running

• University of Wisconsin-Milwaukee — Milwaukee, Wisconsin, United States (enrolling)

Full record on ClinicalTrials.gov

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