Study of Risk Factors and Prediction of Blood Clots After Lung Cancer Surgery
Recruiting now
Conditions studied: Lung Cancer (Diagnosis), Deep Vein Thrombosis (DVT), Venous Thromboembolism (VTE)
In brief
The goal of this observational study is to learn about the risk factors and prediction of postoperative venous thromboembolism (VTE) in patients undergoing lung cancer surgery. The main question it aims to answer is: Which clinical, surgical, and laboratory factors are associated with the development of postoperative deep vein thrombosis (DVT) in lung cancer surgery patients, and can machine learning models accurately predict individual risk? Participants undergoing lung cancer surgery will be prospectively followed for 30 days after surgery. Perioperative clinical data, laboratory results, and imaging findings will be collected to identify VTE risk factors and to develop a predictive model.
Key facts
- Study ID
- NCT07439991
- Run by
- The First Hospital of Jilin University
- People needed
- 900
- Starts
- 2024-11-01
- Expected to finish
- 2029-11-30
- Last updated by the study team
- 2026-02-27
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥ 18 years
- Patients undergoing surgical resection for lung cancer
- Postoperative hospital stay ≥ 48 hours
- Availability of perioperative clinical, laboratory, and imaging data
- Willingness to provide informed consent and participate in 30-day follow-up
You may not qualify if…
- Pre-existing deep vein thrombosis (DVT) or pulmonary embolism (PE) before surgery
- Preoperative or ongoing anticoagulation therapy for ≥ 2 weeks
- Severe coagulation disorders or bleeding diseases
- Severe hepatic, renal, or hematologic dysfunction, or uncontrolled systemic infection
- Concurrent major organ surgery (e.g., cardiac, liver surgery)
- Pregnancy or lactation
- Incomplete postoperative follow-up data
Where it is running
- The First Hospital of Jilin University, Department of Thoracic Surgery — Changchun, Jilin, China (enrolling)
Full record on ClinicalTrials.gov
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