Comparison of Root Canal Desinfection Protocols

Recruiting now · Not applicable

Conditions studied: Periapical Periodontitis

In brief

Evaluate and compare the disinfecting efficacy of two supplementary antimicrobial protocols in teeth with apical periodontitis

Key facts

Study ID

NCT07439614

Run by

State University of New York at Buffalo

People needed

50

Starts

2026-04-01

Expected to finish

2027-06-01

Last updated by the study team

2026-06-23

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adult patients able to give informed consent and willing/able to comply with study procedures and follow-up.
• Molar teeth indicated for endodontic treatment.
• Teeth with intact pulp-chamber walls (no extensive coronal destruction).
• Necrotic pulp confirmed by pulp testing.
• Clinical and radiographic evidence of asymptomatic apical periodontitis.

You may not qualify if…

• Immature teeth
• Teeth with calcified or obliterated canals
• Teeth with extensive coronal destruction
• Teeth with previous endodontic treatment
• Symptomatic apical periodontitis
• Teeth with periodontal pockets greater than 4 mm
• Patients who have received systemic antibiotics in the last 3 months
• Patients with a history of diabetes or immune impairment
• Pregnant patients

Where it is running

• Advance Education in Endodontics Program — Buffalo, New York, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.