Septic Shock Hemodynamic Respond to Volume Resuscitation Versus Vasopressor Administration
Starting soon
Conditions studied: Septic Shock
In brief
The goal of this observational study is to learn about the change of hemodynamic response from intravenous fluid versus medical (vasopressor) resuscitation by echocardiogram in septic shock patient. The main question it aims to answer is: How hemodynamic response change from intravenous fluid versus medical (vasopressor) resuscitation by echocardiogram in septic shock patient? Participants already receiving the appropriate resuscitation at that time by their medical staff as part of their regular medical care for septic shock. The echocardiogram will assess before and after resuscitation.
Key facts
- Study ID
- NCT07438301
- Run by
- Mahidol University
- People needed
- 180
- Starts
- 2026-03-15
- Expected to finish
- 2028-01-31
- Last updated by the study team
- 2026-02-27
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult patients aged ≥18 years
- Diagnosis with Septic Shock (Sepsis-3 Definition of Septic Shock)
- Hypotension, SBP < 90 mmHg, or mean arterial BP < 65 mmHg
You may not qualify if…
- Patients who receive two or more vasopressors
- Patients who receive inotropic medications
- Patients who receive simultaneously fluid with vasopressor resuscitation
- Patients with insufficiently quality ultrasound images for determining echocardiography
- Patients or their legally authorized representatives (LAR), who decline participation in the study or are unable to provide informed consent before enrollment
Where it is running
- Siriraj Hospital — Bangkok, Thailand
Full record on ClinicalTrials.gov
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