Antibacterial Effect and Postoperative Pain After Triton Irrigation Protocol in Necrotic Mandibular Molar
Starting soon · Not applicable
Conditions studied: Pulp Necrosis
In brief
This randomized clinical study evaluates the antibacterial effectiveness and postoperative pain following root canal irrigation using the Triton irrigation protocol in necrotic mandibular molars. Thirty-six patients requiring root canal treatment will be included. The study aims to compare bacterial reduction and postoperative pain outcomes after treatment. Results may help improve irrigation protocols and patient comfort during endodontic therapy.
Key facts
- Study ID
- NCT07435883
- Run by
- sara hosny mostafa
- People needed
- 36
- Starts
- 2026-03-01
- Expected to finish
- 2026-10-01
- Last updated by the study team
- 2026-02-27
Who can join
Age: 18 and older, up to 45. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients aged 18-45 years with no sex predilection
- Medically free Patients with no systemic conditions that can affect post operative pain response.
- Patients should not be taking any pain medications 24 hours before intervention
- Positive patients' acceptance for participating in the study
- Patient able to sign informed consent
- Permanent mandibular molars diagnosis with pulpal necrosis with asymptomatic apical periodontitis.
- Mandibular molars without any anatomical variations or severe curvatures with mesial roots configuration weine class 3 and a distal root with 2 distal canals
You may not qualify if…
- Medically compromised patients
- Patients who have received antibiotic therapy within the last 2 weeks.
- Pregnant or lactating women.
- Patients with known allergy to any of the irrigants used.
- Patients with swelling or acute peri-apical abscess or fistulous tract.
- Teeth that have:
- Wide or open apex .
- Vital pulp tissue .
Where it is running
- Faculty of Oral and Dental Medicine , Future University in Egypt — Cairo, New Cairo, Egypt
Full record on ClinicalTrials.gov
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