CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis

Recruiting now · Not applicable

Conditions studied: Cardiac Amyloidosis, Chest Pain

In brief

The objective of this observational, prospective study is to determine the prevalence of Cardiac Amyloidosis (CA) in males over the age of 65 who experience chest pain but show no signs of coronary artery disease (CAD). Prior to inclusion, all patients will have undergone a CT coronary angiogram or an Rb-PET scan to rule out the possibility of CAD. Participants will be subject to several examinations, including blood tests, urine samples, ECG, echocardiography, and bone scintigraphy. An endomyocardial biopsy may be conducted if necessary.

Key facts

Study ID

NCT07435168

Run by

Rigshospitalet, Denmark

People needed

300

Starts

2024-04-01

Expected to finish

2027-04-01

Last updated by the study team

2026-02-27

Who can join

Age: 65 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• No signs of CAD through Rb-PET and/or CT coronary arteriogram

You may not qualify if…

• Previous history of amyloidosis

Where it is running

• Rigshospitalet — Copenhagen, Denmark (enrolling)

Full record on ClinicalTrials.gov

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