Heparin-binding Protein and Lungedema in ICU Patients.

Recruiting now

Conditions studied: Lung Edema

In brief

The goal of this single center observational cohort study is to investigate the relationship between physiological measures of lung oedema, and the biomarker Heparin-binding Protein (HBP). The main questions it aims to answer are: * Does the concentration of HBP in plasma correlate with measures of lung vascular permeability and extravascular water in the lungs? * Does the concentration of HBP in plasma correlate with the patient's total accumulated fluid balance? Researchers will collect blood samples and gather information on lung vascular permeability and extravascular lung water in Intensive care patients who are provided with a hemodynamic surveillance system called PiCCO. The study will include 25 patients.

Key facts

Study ID

NCT07434908

Run by

Umeå University

People needed

25

Starts

2024-05-06

Expected to finish

2026-07-01

Last updated by the study team

2026-03-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients >18 years
• Monitored with a PiCCO system

You may not qualify if…

• Patients transferred from another ICU

Where it is running

• ICU — Östersund, Sweden (enrolling)

Full record on ClinicalTrials.gov

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