Exercise Timing and Postprandial Glucose Responses

Recruiting now · Not applicable

Conditions studied: Exercise Timing, Postprandial Glucose

In brief

This interventional crossover study examines the effect of exercise timing relative to meal intake on postprandial glucose responses in healthy, physically active young adults. Participants complete five experimental conditions involving endurance exercise performed before or after breakfast or dinner, as well as a non-exercise control condition, while wearing a continuous glucose monitoring device. Postprandial glucose responses are assessed for the three consecutive meals following each exercise session. Following morning exercise, outcomes are assessed after breakfast, lunch, and dinner on the same day. Following evening exercise, outcomes are assessed after dinner on the same day and after breakfast and lunch on the subsequent day. All meals are standardized and consumed at fixed clock times.

Key facts

Study ID

NCT07434349

Run by

Technical University of Munich

People needed

30

Starts

2026-04-01

Expected to finish

2026-08-01

Last updated by the study team

2026-04-20

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18 to 35 years
• Body mass index 18.5 to 24.9 kg per square meter
• Able to complete 45 minutes of continuous running at an intensity corresponding to 75 to 85 percent of maximal heart rate without stopping
• Engages in regular endurance-type physical activity
• Habitual waking times are compatible with the fixed breakfast time of 08:00
• Willing and able to comply with all study procedures, including standardized meals, exercise sessions, behavioral restrictions, and continuous glucose monitoring
• For female participants: non-pregnant and using stable hormonal contraception for at least 3 months

You may not qualify if…

• Acute or chronic illness
• Metabolic disorders or conditions associated with altered glucose or lipid metabolism
• Use of medications known to interfere with glucose metabolism or study outcomes
• Intolerance or allergy to components of the standardized study diets
• Pregnancy or breastfeeding
• Body mass index greater than or equal to 25 kg per square meter
• Current or past eating disorder, or any medical condition or medication that could affect appetite regulation, glucose regulation, or make vigorous endurance exercise unsafe
• Current smoking or use of nicotine-containing products

Where it is running

• Technical University of Munich — München, Bavaria, Germany (enrolling)

Full record on ClinicalTrials.gov

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