Adding Magnesium Sulfate to Combined Pecto-Intercostal & Serratus Anterior Planes Block on Post-operative Analgesia in Patients Undergoing Modified Radical Mastectomy
Starting soon · Not applicable
Conditions studied: Modified Radical Mastectomy
In brief
Here, in our study, we intend to compare the analgesic efficacy of magnesium sulfate as an adjuvant to local anesthetics added to the Pecto-Intercostal Fascial Block (PIFB) vs the Serratus Anterior Plane Block (SAPB) in patients undergoing modified radical mastectomy. Study Endpoints Primary Endpoints: Total intravenous opioid consumption during the first 24 hours following surgery. Secondary Endpoints: Postoperative analgesia, 24 hours after surgery, assessed using the Visual Analog Scale (VAS) and time to first analgesic request.
Key facts
- Study ID
- NCT07434232
- Run by
- South Egypt Cancer Institute
- People needed
- 100
- Starts
- 2026-02-15
- Expected to finish
- 2027-04-15
- Last updated by the study team
- 2026-02-25
Who can join
Age: 30 and older, up to 75. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Female patients aged 30 to 75 years diagnosed with non-metastatic breast cancer and scheduled for modified radical mastectomy.
- ASA, I-III and NYHA, I-II.
- Written informed consent.
You may not qualify if…
- ASA physical status >III and NYHA >II,
- body mass index >40 kg/m2,
- pregnant women,
- Patients with organ failure or coagulation disorders.
- Allergy to local anesthetics or magnesium sulfate
- Contraindications as local infection
- History of chronic pain or opioid use .
- Unwilling to participate in the study
Full record on ClinicalTrials.gov
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