Time to BBVNA Relief

Recruiting now

Conditions studied: Low Back Pain, Vertebrogenic Pain Syndrome, Basivertebral Nerve Ablation

In brief

Basivertebral nerve ablation (BVNA) is a minimally invasive procedure approved for vertebrogenic low back pain. While early studies support its efficacy, real-world evidence is still evolving, particularly regarding the trajectory of pain relief and functional improvement over time, and predictors of clinical response. This study aims to evaluate clinical outcomes longitudinally following BVNA and identify baseline predictors of response.

Key facts

Study ID: NCT07433634
Run by: Yale University
People needed: 200
Starts: 2024-04-19
Expected to finish: 2026-10-01
Last updated by the study team: 2026-03-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Diagnosis of chronic axial low back pain with vertebrogenic features
Scheduled for BVN ablation
Able to provide informed consent
Capable of participating in weekly virtual/telephone follow-up for 8 weeks and in- person or remote follow-up at 3 and 6 months through 2 years

You may not qualify if…

Prior spinal neuromodulation therapy (e.g., spinal cord stimulation or intrathecal pump) within the past 6 months
Active substance use disorder or uncontrolled psychiatric illness that may interfere with participation
Cognitive impairment limiting ability to complete surveys or provide informed consent
Pregnancy
Incarceration or current status as a prisoner

Where it is running

Yale Spine and Pain Center - Guilford — Guilford, Connecticut, United States (enrolling)
Yale Pain Management Center - New Haven — New Haven, Connecticut, United States (enrolling)
Yale Interventional Spine and Musculoskeletal Medicine - Old Saybrook — Old Saybrook, Connecticut, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.