Mechanical Power and Driving Pressure Exposure in Laparoscopic Surgery
Starting soon
Conditions studied: Postoperative Pulmonary Complications
In brief
Postoperative pulmonary complications (PPCs) remain an important cause of morbidity after abdominal surgery. Intraoperative mechanical ventilation may contribute to lung injury through the mechanical load applied to the respiratory system. Mechanical power (MP) and driving pressure (DP) have emerged as integrative parameters reflecting the total ventilatory burden delivered to the lungs. This prospective observational study aims to evaluate the association between time-dependent exposure to intraoperative mechanical power and driving pressure and postoperative pulmonary outcomes in patients undergoing elective laparoscopic abdominal surgery. Ventilatory parameters will be recorded at predefined intervals during routine clinical care, and MP and DP will be calculated without altering clinical management. The primary objective is to assess whether longer exposure to elevated ventilatory load is associated with the development of postoperative pulmonary complications.
Key facts
- Study ID
- NCT07431242
- Run by
- Istinye University
- People needed
- 90
- Starts
- 2026-02-25
- Expected to finish
- 2026-07-15
- Last updated by the study team
- 2026-02-24
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥ 18 years
- Scheduled for elective laparoscopic abdominal surgery under general anesthesia
- Intraoperative mechanical ventilation with volume-controlled ventilation
- Provision of written informed consent
You may not qualify if…
- Emergency surgery
- Conversion to open surgery
- Preoperative invasive or noninvasive mechanical ventilation
- Intraoperative major complications requiring substantial deviation from routine ventilation management
- Incomplete intraoperative or postoperative data
- Refusal or inability to provide informed consent
Where it is running
- Istinye Üniversity — Istanbul, Merkez Mahallesi, Turkey (Türkiye)
Full record on ClinicalTrials.gov
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