Efficacy of Gabapentin Combined With Solifenacin for Non-neurogenic Overactive Bladder in Women

Starting soon · Phase 3

Conditions studied: Overactive Bladder

In brief

The goal of the study is to compare the efficacy, safety and tolerability of solifenacin plus gabapentin versus solifenacin monotherapy for the treatment of women who are suffering from non-neurogenic ОАВ. The main questions it aims to answer are: Does combination of Solifenacin and Gabapentin affect the total score and sub-scores of OABSS in females with non-neurogenic ОАВ ? What medical problems do participants have when taking combination of Solifenacin and gabapentin ?

Key facts

Study ID

NCT07429734

Run by

Mansoura University

People needed

60

Starts

2026-02-01

Expected to finish

2027-01-01

Last updated by the study team

2026-02-24

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Overactive bladder symptom score (OABSS) > 5, urgency subscore ≥3, and urge incontinence score≥ 2.

You may not qualify if…

• Active urinary tract infection
• Neurogenic bladder
• History of genitourinary malignancy
• Stress urinary incontinence (SUI) as primary diagnosis, or mixed urinary incontinence with predominant SUI
• Any psychological or psychiatric disorders

Where it is running

• Urology and Nephrology center - Mansoura University — Al Mansurah, Egypt

Full record on ClinicalTrials.gov

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