SAD and MAD Study of AKB-9090 in Healthy Adult Participants

Recruiting now · Phase 1 · Has a placebo group

Conditions studied: Healthy Volunteers

In brief

This is a first-in-human (FIH study designed to evaluate safety, tolerability, pharmacokinetic, and pharmacodynamic effects of AKB-9090 in healthy adult participants. The study consists of two stages: Stage 1, a single ascending dose (SAD) phase with five dose cohorts, and Stage 2, a multiple ascending dose (MAD) phase with three dose cohorts. Approximately 40 participants in SAD and 30 in MAD are planned to be enrolled.

Key facts

Study ID
NCT07429006
Run by
Akebia Therapeutics
People needed
70
Starts
2026-03-16
Expected to finish
2026-12-01
Last updated by the study team
2026-04-13

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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