Feasibility of Intradialytic Monitoring During CKRT

Enrolling by invitation

Conditions studied: Acute Kidney Injury, End Stage Chronic Renal Failure, Dialysis

In brief

This is a pilot observational cohort study to understand whether advanced monitoring techniques can be applied during continuous kidney replacement therapy (CKRT), which is the most common form of dialytic therapy provided in critically ill patients.

Key facts

Study ID

NCT07428395

Run by

University of Pennsylvania

People needed

30

Starts

2026-03-17

Expected to finish

2028-03-01

Last updated by the study team

2026-05-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients who have been admitted to the Medical ICU or Cardiothoracic ICU at the Hospital of the University of Pennsylvania (HUP).
• Patients who have been prescribed continuous venovenous hemodialysis (CVVHD) or Continuous Veno-Venous Hemofiltration (CVVH), the predominant modalities of continuous kidney replacement therapy (CKRT) at HUP.
• Patients who have central venous catheters placed in either the left or right internal jugular veins.

You may not qualify if…

• Patients who are prescribed other forms of CKRT, namely continuous venovenous hemofiltration (CVVH), slow continuous ultrafiltration (SCUF), or prolonged intermittent kidney replacement therapy (PIKRT).
• Patients who have femoral vein dialysis catheters placed.
• Patients who cannot provide consent or have a legal proxy to provide consent.

Where it is running

• University of Pennsylvania — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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