Retinopathy of Prematurity - Visual Function and Retinal Structure

Starting soon

Conditions studied: Retinopathy of Prematurity (ROP), Prematurity Complications, Cerebral Visual Impairment, Visual Field Defect

In brief

Children born prematurely may develop a characteristic retinal disease named retinopathy of prematurity (ROP). This disease could lead to retinal detachment and blindness. ROP was traditionally treated with laser, but injection with a medication (A-VEGF) has become more common. In this study, the researchers will explore whether treatment of ROP affects visual function and retinal development. To explore this, the study group will examine children with ROP (but not treated) with children treated with either laser or injection. The researchers will compare the children's visual functions (e.g. visual acuity and visual field) and their retinas (e.g. central and peripheral retina).

Key facts

Study ID

NCT07427719

Run by

Oslo University Hospital

People needed

140

Starts

2026-04-01

Expected to finish

2029-06-01

Last updated by the study team

2026-02-23

Who can join

Age: 6 and older, up to 20. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients treated for ROP with either laser or injection of A-VEGF.
• Patients previously diagnosed with ROP but not treated for the condition.

You may not qualify if…

• Age below six years at date of examination.
• A developmental level not compatible with performing the study examinations.
• Patients born or treated outside Norway
• Known ocular or systemic disease that can give structural or functional changes in the retina.

Where it is running

• Oslo University Hospital — Oslo, Oslo, Norway

Full record on ClinicalTrials.gov

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