Attenuate the Stress Response in Laparoscopic Cholecystectomy

Starting soon · Phase 4

Conditions studied: Laparoscopic Cholecystectomy Surgery

In brief

Aims of this study are to compare the effectiveness of dexmedetomidine versus fentanyl-midazolam in attenuating hemodynamic stress response during laparoscopic cholecystectomy (mainly HR). And to assess the recovery profile, the pain and opioid requirements, the sedation profile, and any adverse events during the first 24 hrs postoperatively

Key facts

Study ID

NCT07425444

Run by

Assiut University

People needed

50

Starts

2026-02-01

Expected to finish

2027-04-01

Last updated by the study team

2026-02-20

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-65 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I - II.

You may not qualify if…

• Known allergy to study drugs.
• Uncontrolled, non-correctable comorbidities (hepatic, renal or cardiac such as hypertension \& Arrhythmia ).
• History of psychiatric illness or substance abuse.
• Pregnancy or lactation

Full record on ClinicalTrials.gov

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