A Study of Tris-Hydroxymethyl Aminomethane (THAM) Versus Sodium Bicarbonate in Cardiac Surgical Patients
Starting soon · Phase 4
Conditions studied: Metabolic Acidosis
In brief
The purpose of this research is to determine if two commonly used medications to treat metabolic acidosis in the setting of cardiac surgery, sodium bicarbonate and THAM, are equivalent.
Key facts
- Study ID
- NCT07424625
- Run by
- Mayo Clinic
- People needed
- 250
- Starts
- 2026-09-01
- Expected to finish
- 2028-06-01
- Last updated by the study team
- 2026-08-03
Who can join
Age: 21 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mayo Clinic — Rochester, Minnesota, United States
Full record on ClinicalTrials.gov
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