Effect of Dexmedetomidine Versus Dexamethasone as Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Plane Block on Postoperative Analgesia in Myasthenic Patients Undergoing Thoracoscopic Thymectomy
Starting soon · Not applicable
Conditions studied: Postoperative Pain, Acute
In brief
This current comparative study involved 54 patients undergoing thoracoscopic thymectomy who were distributed randomly into three equal groups to receive ultrasound (US)-guided ESPB using 20 ml bupivacaine 0.25% (group B) , 20 ml bupivacaine 0.25% with 8 mg dexamethasone (group BS), 20 ml bupivacaine 0.25% with dexmedetomidine 1mcg/kg (group BM). The time till the first postoperative rescue analgesic requested was the primary outcome. The secondary outcomes included the postoperative pain scores and analgesic consumption.
Key facts
- Study ID
- NCT07424599
- Run by
- Ain Shams University
- People needed
- 60
- Starts
- 2026-03-15
- Expected to finish
- 2026-09-15
- Last updated by the study team
- 2026-02-20
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- myasthenic patients
- American Society of Anesthesiologists (ASA) physical grade of 2-3)
- who underwent video assisted thoracoscopic thymectomy
You may not qualify if…
- Refused participation in the study,
- known allergy for this study drugs ,
- Contraindication to the ESPB as infection at block site \& marked chest cage deformity,
- significant bleeding disorders ,
- patients with significant renal or liver dysfunction,
- heart block ,
- poor ventilatory function,
- severe chronic obstructive pulmonary disease,
- morbid obesity,
- mental disability, or communication difficulties that hindered effective pain assessment,
- Individuals who was converted to open thoracotomy or those re-explorated for surgical related issues.
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.