REMIDEP-HTA Program for Hypertension Remission and Medication Deprescription

Starting soon · Not applicable

Conditions studied: Essential Hypertension

In brief

The REMIDEP-HTA trial is a multicenter randomized controlled study designed to evaluate whether a structured approach combining an intensive lifestyle intervention with a systematic deprescribing algorithm can achieve clinical remission of essential hypertension. \<br\>\<br\> The intervention integrates a 12-week high-intensity behavioral program focused on whole-food plant-based nutrition, progressive physical activity, sleep hygiene, and stress management, together with a hierarchical, safety-centered medication tapering protocol for antihypertensive therapy. \<br\>\<br\> The study aims to determine whether remission can be achieved through a standardized and monitored strategy that prioritizes clinical safety during medication withdrawal.

Key facts

Study ID
NCT07424118
Run by
Evelyn Vanina Re
People needed
240
Starts
2026-04-01
Expected to finish
2026-12-01
Last updated by the study team
2026-02-20

Who can join

Age: 40 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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