Effect of Graphene Oxide on Vital and Non-Vital Primary Teeth Compared to the Conventional Techniques

Starting soon · Not applicable

Conditions studied: Primary Teeth Indicated for Pulp Therapy

In brief

The null hypothesis of the current study suggested that there will be no significant difference regarding the effect of Graphene Oxide (GO), Lesion sterilization and tissue repair (LSTR) and Zinc Oxide and Eugenol on the clinical and radiographic success rate of non-vital pulpotomy of primary teeth and that there will be no significant difference regarding the effect of Graphene Oxide (GO), MTA and Zinc Oxide and Eugenol on the clinical and radiographic success rate of vital pulpotomy of primary teeth. The children (n=126) will be divided randomly into 2 arms; each arm has 3 groups, according to the type of pulp therapy dressing, medicament,t and technique of its application as follows: First Arm (Vital Teeth) Group 1: will receive Graphene Oxide using the vital pulpotomy technique (study group, n=21) Group 2: will receive MTA using vital pulpotomy technique (study group, n=21) Group 3: will receive Zinc Oxide and Eugenol using the vital pulpotomy technique (control group, n=21) Second Arm (Non-Vital Teeth) Group A: will receive Graphene Oxide using the non-vital pulpotomy technique (study group, n=21). Group B: will receive LSTR using the non-vital pulpotomy technique (study group, n=21). Group C: will receive Zinc Oxide and Eugenol using non-vital pulpotomy (Control group, n=21). Clinical and radiographic success will be assessed as primary outcomes, while pain, patient satisfaction,n and time of procedure will be assessed as secondary outcomes.

Key facts

Study ID

NCT07424053

Run by

Al-Azhar University

People needed

126

Starts

2026-04-01

Expected to finish

2026-12-01

Last updated by the study team

2026-02-20

Who can join

Age: 5 and older, up to 10. Sex: any. Healthy volunteers: not accepted.

Full record on ClinicalTrials.gov

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