Effect of a Low-Calorie MCT-Rich Traditional Minangkabau Diet on Obese Individuals
Starting soon · Not applicable
Conditions studied: Metabolically Unhealty Obese, Dyslipidemia, Diabetes (DM), Resistance, Insulin, Obesity
In brief
This study aims to investigate the effect of a low-calorie diet rich in medium-chain triglycerides (MCTs) based on traditional Minangkabau foods on metabolic biomarkers in individuals with obesity. The traditional Minangkabau foods used in this study consist primarily of coconut milk-based dishes, which contain coconut oil as a natural source of MCTs. The metabolic biomarkers assessed include body mass index (BMI), waist circumference, systolic and diastolic blood pressure, body fat percentage, fasting blood glucose levels, lipid profile, leptin concentrations, and DNA methylation of the leptin gene promoter. Based on these metabolic biomarker measurements, participants will be classified into metabolic obesity phenotypes, namely metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUHO). The researchers hypothesize that the provision of a low-calorie, MCT-rich diet based on traditional Minangkabau foods will have a significant effect on metabolic biomarkers and metabolic status in individuals with obesity.
Key facts
- Study ID
- NCT07423884
- Run by
- Andalas University
- People needed
- 40
- Starts
- 2026-04-01
- Expected to finish
- 2026-07-01
- Last updated by the study team
- 2026-04-13
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Administrative staff of the Faculty of Medicine and the Faculty of Public Health, Andalas University, Padang, with obesity defined as a body mass index (BMI) ≥ 25 kg/m².
- Willing to participate in the study by providing written informed consent.
- Participants with obesity classified as Metabolically Unhealthy Obese (MUHO)
You may not qualify if…
- Did not come and could not be found at the time of research data collection
- Unable to follow the dietary arrangements as set
- Taking anti-diabetic or anti-lipid drugs
- Use of contraceptives or hormonal drugs
- In the treatment of radiotherapy or chemotherapyi
- Participants with obesity classified as Metabolically Healthy Obese (MHO)
Where it is running
- Prof. Nur Indrawaty Lipoeto — Padang, West Sumatera, Indonesia
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.