Impact of Cannabis Use During Third Molar Surgery

Recruiting now

Conditions studied: Cannabis Use, Marijuana Usage, Sedation and Analgesia, Wisdom Tooth

In brief

This study is for people scheduled to have their wisdom teeth (third molars) removed and are going to receive drug through an IV to put them to sleep. The researchers are studying two groups: one group of people who report using recreational marijuana/THC/cannabis and another group who report not using it. They want to look at how both users and non-users do during the tooth removal.

Key facts

Study ID

NCT07423195

Run by

University of Michigan

People needed

242

Starts

2026-01-14

Expected to finish

2030-01-01

Last updated by the study team

2026-02-20

Who can join

Age: 16 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Provide a signed and dated informed consent form.
• Willing to comply with all study procedures and be available for the duration of the study.
• Aged ≥ 16 years old.
• Presence at least one mandibular 3rd molar
• American Society of Anesthesiologists (ASA) physical status class I or II

You may not qualify if…

• Pathology (cyst or tumor) associated with the third molar tooth;
• Health comorbidities (BMI 40 and above, and severe cardiovascular disease);
• Pregnancy or lactation
• Anything that would place the individual at increased risk or preclude the individual's full compliance with or completion of the study.

Where it is running

• University of Michigan School of Dentistry/ Oral and Maxillofacial Surgery — Ann Arbor, Michigan, United States (enrolling)

Full record on ClinicalTrials.gov

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