Menopausal Impact of Opportunistic Salpingectomy for Ovarian Cancer Prevention
Starting soon · Not applicable
Conditions studied: Menopause, Opportunistic Salpingectomy
In brief
The goal of this clinical trial is to find out whether removing the fallopian tubes at the time of hysterectomy leads to an earlier menopause. The study includes women under 55 years of age who previously underwent hysterectomy as participants in the HOPPSA trial, where they were randomly assigned to either removal of the fallopian tubes or no removal. The main question is: • Does removing the fallopian tubes at the time of hysterectomy lead to an earlier menopause? Researchers will compare women who had their fallopian tubes removed during hysterectomy with women who had hysterectomy alone to see whether menopause occurs earlier after tube removal. Age at menopause will be estimated by measuring follicle-stimulating hormone (FSH) in small blood samples collected on a paper card. Participants will: * Collect 4-5 drops of blood using a finger prick * Place the drops on a paper card and mail it to the researchers * Complete an online questionnaire These steps will be done twice, one year apart.
Key facts
- Study ID
- NCT07423143
- Run by
- Umeå University
- People needed
- 2100
- Starts
- 2026-03-01
- Expected to finish
- 2057-12-01
- Last updated by the study team
- 2026-02-20
Who can join
Age: 20 and older, up to 65. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Having had hysterectomy for a benign indication
- Less than 55 years at surgery
- Was included in the ITT population of the HOPPSA register-based randomised controlled trial (R-RCT) of opportunistic salpingectomy
- Informed consent
You may not qualify if…
- Ongoing systemic hormonal treatment using sex steroids
- Bilateral oophorectomy
- Cancer treatment affecting ovarian function
- Other treatments with major effects on ovarian function
Where it is running
- Umeå University — Umeå, Sweden
Full record on ClinicalTrials.gov
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