Dynamic Network Response to TMS Treatment
Recruiting now
Conditions studied: MDD
In brief
This project aims to investigate whether symptom and brain networks and TMS stimulation sites can predict the response to TMS treatment of a transdiagnostic patient group with depressive syndrome. The TMS treatment is no intervention study - the investigators aim to observe patients who receive TMS as part of their psychiatric treatment. Additionally, the investigators aim to investigate exploratively how symptoms change over the course of treatment with TMS, that is, which symptoms respond first to treatment. Patients participate in a separate study first (DYNAMIC Central Project, registered with the German Clinical Trials Register: DRKS00038256), where MRI data is acquired. Within this project the symptomatology before, during and after the TMS-treatment are observed.
Key facts
- Study ID
- NCT07422844
- Run by
- Goethe University
- People needed
- 100
- Starts
- 2025-11-24
- Expected to finish
- 2031-12-31
- Last updated by the study team
- 2026-02-20
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients who are treated with TMS as an antidepressant will be recruited for study participation. The TMS treatment is carried out regardless of study participation.
- Men and women will be included in a balanced ratio.
- German language skills are required to ensure that questionnaires, interviews, and instructions are correctly understood, processed and answered.
You may not qualify if…
- Patients younger than 18 or older than 70 will be excluded
- Participants who did not participate in the DYNAMIC central project (German Clinical Trials Register DRKS00038256) will be excluded.
- Further exclusion criteria for participation are acute or chronic neurological diseases.
- Patients who are pregnant will not be included in the study.
- As we use app-based questionnaires, we cannot include participants without internet-enabled devices in the study.
Where it is running
- Klinik für Psychiatrie, Psychosomatik und Psychotherapie — Frankfurt am Main, Hesse, Germany (enrolling)
Full record on ClinicalTrials.gov
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