Prospective Registry of Vertigo Due to Vertebrobasilar Transient Attacks.
Starting soon
Conditions studied: Vertigo, Dizziness, TIA (Transient Ischemic Attack), Transient Neurologic Symptoms
In brief
Vertigo and dizziness are common neurological complaints in the emergency department and may represent a wide spectrum of etiologies, including vertebrobasilar transient neurological attacks (VB-TNAs). Distinguishing VB-TNAs, particularly vertebrobasilar transient ischemic attacks (VB-TIAs), from migraine-like and other non-vascular conditions is often challenging at first presentation due to the absence of specific biomarkers and overlapping clinical features. The UTRAVERA study is a multicenter, prospective, observational investigation designed to characterize the clinical features of patients presenting with acute transient vertigo or dizziness suspected to be VB-TNAs. The study will also evaluate diagnostic evolution over time, treatment responses, and prognostic factors associated with clinical outcomes.
Key facts
- Study ID
- NCT07421973
- Run by
- University of Sao Paulo General Hospital
- People needed
- 400
- Starts
- 2026-05-01
- Expected to finish
- 2028-10-01
- Last updated by the study team
- 2026-02-27
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Episodic acute vertigo, dizziness or unsteadiness transient or in evolution, therefore, lasting <24 h
- Such an episode may be isolated or associated with one or more of the following:
- focal central neurological symptoms or severe postural instability;
- new-onset, moderate-to-severe craniocervical pain; or
- symptoms that are not better accounted for by another disease or disorder.
You may not qualify if…
- Patients who present with findings of acute hemorrhage or ischemia on the cranial magnetic resonance imaging (MRI), including diffusion-weighted MRI (DWI-MRI) at recruitment;
- Patients who also fulfill the diagnostic criteria for other neurotological diseases that may present acute or recurrent transient dizziness/Vertigo (Unilateral Vestibulopathy; benign paroxysmal positional vertigo; Meniére's disease; Vestibular Migraine; Vestibular Paroxysmia; Persistente Postural-Perceptual Dizziness; and Postural Hypotension;
- Patients whose symptoms last more than 24 hours or who have evidence of sequelae during follow-up;
- Patients with contraindications to any of the therapeutic options proposed by this study method;
- Patients who have other symptoms during the follow-up that suggest another etiology of dizziness or vertigo;
- Patients who do not complete the entire evaluation;
- Patients who refuse to sign the informed consent form.
Where it is running
- Hospital das Clínicas - University of São Paulo — São Paulo, São Paulo, Brazil
Full record on ClinicalTrials.gov
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