Comparison of Two Different Doses of Phenylephrine on Oxytocin Hemodynamic Effect

Recruiting now · Phase 4

Conditions studied: Phenylephrine, Cesarean Birth

In brief

Cesarean section is one of the commonly performed surgical procedures in the world. Once baby is delivered during the surgical procedure anesthesiologist administer Oxytocin drug through IV cannula which helps the Uterus to contract so that excessive blood loss doesnt occur. But this is associated with fall in blood pressure frequently requiring administration of medications to treat low blood pressure. The most frequently used drug is phenylephrine which can administered along with oxytocin to prevent fall in blood pressure. This study will compare to different doses of Phenylephrine to prevent fall in blood pressure.

Key facts

Study ID

NCT07420127

Run by

Rawalpindi Medical College

People needed

112

Starts

2026-02-13

Expected to finish

2026-07-13

Last updated by the study team

2026-02-24

Who can join

Age: 20 and older, up to 40. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Females having a singleton pregnancy Patients planned for elective cesarean section under spinal anesthesia

You may not qualify if…

• Patients having a placental abnormality
• Patients taking beta-blocker and vasodilator therapy
• Patients with hypertensive disorder

Where it is running

• Department of Anesthesia, Holy Family Hospital, Rawalpindi — Rawalpindi, Punjab Province, Pakistan (enrolling)

Full record on ClinicalTrials.gov

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