Dental Plaque Prevention Efficacy of a Stannous Fluoride Toothpaste

Completed · Not applicable

Conditions studied: Dental Plaque

In brief

This randomized, stratified, double-blind, two-cell parallel clinical study evaluated the dental plaque prevention efficacy of a stannous fluoride toothpaste compared to a sodium fluoride control toothpaste following a professional dental prophylaxis. Adult subjects brushed twice daily for 14 days with their assigned dentifrice. Plaque was assessed using the Lobene-Soparkar modification of the Turesky Modification of the Quigley-Hein Plaque Index at baseline, Day 1, and Day 14 following periods of oral hygiene abstention.

Key facts

Study ID

NCT07419737

Run by

Church & Dwight Company, Inc.

People needed

91

Starts

2024-10-16

Expected to finish

2024-12-04

Last updated by the study team

2026-02-19

Who can join

Age: 18 and older, up to 69. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Good general health based on medical history
• Minimum of 18 natural teeth with scorable surfaces
• Baseline mean plaque score ≥2.0
• Willing to refrain from non-study oral hygiene products
• Willing to abstain from oral hygiene prior to study visits
• Able and willing to comply with study procedures

You may not qualify if…

• Known allergy to oral care products
• Conditions limiting normal brushing
• Significant medical conditions affecting study participation
• Pregnant or nursing females
• Severe periodontal disease
• Recent dental prophylaxis
• Recent participation in another dental study

Where it is running

• Salus Research, Inc. — Fort Wayne, Indiana, United States

Full record on ClinicalTrials.gov

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