Prognostic Value of Novel Biomarkers on Adverse Renal Outcomes in High-Risk Cardiac Surgery Patients

Recruiting now

Conditions studied: Cardiac Surgery Associated - Acute Kidney Injury, Critical Illness

In brief

This project aims to detect novel biomarkers from preoperative and early postoperative serum and urine samples of patients to screen and analyze the risk factors for predicting adverse postoperative renal outcomes in high-risk patients in cardiac surgery.

Key facts

Study ID

NCT07418242

Run by

Guowei Tu

People needed

1491

Starts

2026-02-23

Expected to finish

2029-05-31

Last updated by the study team

2026-05-18

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• pre-existing chronic kidney disease (preoperative estimated glomerular filtration rate [eGFR] < 30 mL/min/1.73 m2);
• previous RRT before cardiac surgery;
• present AKI at screening;
• a history of kidney transplant or other kidney diseases;
• known pregnancy;
• multiple operation during the hospital stay;
• being in a moribund state (with an anticipated likelihood of death within 48 hours).

Where it is running

• Zhongshan hospital — Shanghai, Shanghai Municipality, China (enrolling)
• Zhongshan hospital, Fudan university — Shanghai, Shanghai Municipality, China

Full record on ClinicalTrials.gov

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