Diagnostic Performance Of 4D Dynamic LAFOV FDG-PET Acquisition for Differentiation of Residual Disease and Post-radiation Inflammation in Head Neck SCC Treated by Radiotherapy.

Recruiting now

Conditions studied: Head & Neck Squamous Cell Carcinoma

In brief

This multicenter prospective observational study will evaluate the value of dynamic FDG-PET LAFOV imaging during the initial therapeutic assessment of a head and neck cancer 3 months after completion of curative radiotherapy.

Key facts

Study ID

NCT07417605

Run by

University Hospital, Brest

People needed

180

Starts

2026-04-13

Expected to finish

2029-06-13

Last updated by the study team

2026-07-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patient ≥ 18 years of age
• Presenting with head and neck squamous cell carcinoma
• Completed curative treatment with external radiation therapy
• Eligible for dynamic LAFOV FDG-PET scan for therapeutic evaluation at 3 months
• Having given consent for the end-of-treatment consultation

You may not qualify if…

• Hypersensitivity to 18F-FDG or other excipients contained in the contrast agent
• Pregnancy or breastfeeding
• History of treated upper gastrointestinal tract cancer
• Other histology
• Incomplete RTE treatment regimen
• Refusal to participate

Where it is running

• CHU Brest — Brest, France (enrolling)
• Centre finistérien de radiothérapie et d'oncologie - site Clinique Pasteur — Brest, France
• Centre finistérien de radiothérapie et d'oncologie - Site de l'hôpital La Cavale Blanche — Brest, France

Full record on ClinicalTrials.gov

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