Cooling of the Knee After Total Knee Arthroplasty

Starting soon · Not applicable

Conditions studied: Osteoarthritis, Knee, Total Knee Replacement

In brief

This study investigates whether cooling the knee after total knee replacement surgery can reduce pain and improve early recovery. After surgery, patients are randomly assigned to one of three groups: cooling with a liquid cooling bandage, cooling with an ice pack, or standard postoperative care without cooling. Cooling begins 24 hours after surgery and continues for two weeks. Pain levels, use of pain medication, blood values, knee swelling, knee movement, and length of hospital stay are recorded. The goal is to determine whether postoperative knee cooling provides additional benefits compared with standard care.

Key facts

Study ID

NCT07416721

Run by

Clinical Center of Vojvodina

People needed

99

Starts

2026-03-01

Expected to finish

2027-03-01

Last updated by the study team

2026-02-18

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• • Adults undergoing primary total knee arthroplasty
• Use of a primary knee prosthesis of identical design in all patients
• Body mass index (BMI) < 35 kg/m²
• Ability to understand the study protocol and comply with postoperative instructions
• Absence of diagnosed mental disease

You may not qualify if…

• • Unregulated or poorly controlled diabetes mellitus
• Rheumatoid arthritis or other inflammatory arthropathies
• Presence of mental disease impairing cooperation or protocol adherence

Full record on ClinicalTrials.gov

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