Comparing PTeye-assisted Versus Conventional Total Thyroidectomy

Recruiting now · Not applicable

Conditions studied: Hypocalcemia, Parathyroid, Hypoparathyroidism Post-surgical, Total Thyroidectomy

In brief

This is a prospective, single-blinded, randomized controlled trial to evaluate whether PTeye™ can reduce post-operative hypoparathyroidism (PH). The study will enroll consecutive patients undergoing total thyroidectomy in a teritary endocrine surgery unit in Hong Kong, randomizing them into receiving conventional surgery versus PTeye™-assisted surgery. Subjects will be assigned to the two groups before surgery. Subjects will be under medical care as in usual practice.

Key facts

Study ID

NCT07416149

Run by

The University of Hong Kong

People needed

210

Starts

2025-09-16

Expected to finish

2028-12-31

Last updated by the study team

2026-02-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients ≥18 years of age
• Undergoing total thyroidectomy, or completion total thyroidectomy
• Pre-operative serum adjusted calcium levels within normal ranges

You may not qualify if…

• Patients on pre-operative calcium or vitamin D supplements
• Patients with pre-operative vitamin D deficiency, defined as serum vitamin D<30nmol/L
• Patients with untreated primary or secondary hyperparathyroidism
• Patient with known non-surgical hypoparathyroidism diseases
• Patients with estimated glomerular filtration rate <30ml/1.73m2/min, on dialysis, or having a history of kidney transplant

Where it is running

• Queen Mary Hospital — Hong Kong, Hong Kong (enrolling)

Full record on ClinicalTrials.gov

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