Cold vs Warm Enteral Feeding and Gastric Emptying in Adult ICU Patients
Enrolling by invitation · Not applicable
Conditions studied: Gastric Emptying, Enteral Nutrition (Food for Special Medical Purposes)
In brief
In critically ill patients receiving enteral nutrition in the intensive care unit, the functional capacity of the gastrointestinal system can be significantly influenced by the mode of nutritional support. The temperature of enteral feeding may exert potential effects on gastric emptying, intestinal motility, and nutrient absorption. However, the existing literature on the impact of feeding temperature is limited, and randomized or cross-over controlled studies directly comparing warm and cold enteral feeding are scarce. This study aims to systematically evaluate the effects of enteral feeding temperature on feeding tolerance (vomiting and aspiration), gastric emptying rate (gastric residual volume), and the incidence of diarrhea, thereby providing evidence to inform clinical practice.
Key facts
- Study ID
- NCT07415616
- Run by
- Bursa Yuksek Ihtisas Training and Research Hospital
- People needed
- 15
- Starts
- 2025-09-01
- Expected to finish
- 2026-08-01
- Last updated by the study team
- 2026-02-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients aged 18 years or older
- Expected length of stay in the intensive care unit of at least 96 hours
- Patients receiving enteral nutrition via a nasogastric tube
- Absence of ileus or active gastrointestinal bleeding
You may not qualify if…
- Patients younger than 18 years of age
- Use of high-dose opioids known to affect gastrointestinal motility
- Patients receiving parenteral nutrition
- Known gastrointestinal diseases or a history of gastrointestinal surgery
- Patients with acute intracranial events will not be included in the study
Where it is running
- Bursa Yuksek Ihtisas Research and Education Hospital — Bursa, Turkey (Türkiye)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.