Muscle Strength Asymmetry In Sarkopenic And Non-sarcopenic Older Adults
Starting soon
Conditions studied: Sarcopenia in Elderly
In brief
The purpose of this observational study is to examine whether differences in muscle strength between the dominant and non-dominant sides of the body are associated with sarcopenia in older adults. The study will include adults aged 65 years and older with and without sarcopenia. Muscle strength will be measured on both sides of the body using handgrip strength as well as strength measurements of the biceps (upper arm muscle) and quadriceps (thigh muscle). The difference in strength between the dominant and non-dominant sides will be calculated and compared between participants with sarcopenia and those without sarcopenia. The main question it aims to answers are: * Do older adults with sarcopenia have larger differences in muscle strength between the two sides of the body compared with those without sarcopenia? * Can differences in arm and leg muscle strength help identify older adults who may be at higher risk of sarcopenia?
Key facts
- Study ID
- NCT07414888
- Run by
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
- People needed
- 140
- Starts
- 2026-02-12
- Expected to finish
- 2026-03-12
- Last updated by the study team
- 2026-03-05
Who can join
Age: 65 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age 65 years or older
- Ability to walk independently or with minimal assistance
- Ability to understand and follow simple instructions
- Willingness and ability to provide written informed consent
- Availability of muscle strength measurements (handgrip, biceps, and quadriceps)
You may not qualify if…
- Lack of cooperation, moderate to severe dementia (e.g., MMSE <24) or conditions impeding cooperation.
- Those with severe cardiovascular disease
- Those with pacemakers
- Surgical/fracture/acute pain in the measured extremities within the last 6 months.
- Neurological and muscular disease affecting the upper or lower extremity (acute stroke, severe peripheral neuropathy, etc.)
- Active systemic disease attack significantly affecting the measurement.
Where it is running
- Istanbul Physical Therapy and Rehabilitation Training and Research Hospital — Istanbul, Bahçelievler, Turkey (Türkiye)
Full record on ClinicalTrials.gov
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