Non-Surgical Periodontal Therapy and Cardiac Biomarkers in Stable Angina

Starting soon · Not applicable

Conditions studied: Stable Angina, Periodontitis

In brief

The goal of this clinical study is to learn whether gum treatment can improve heart health. Researchers will compare blood markers related to heart disease before and after routine gum treatment. The main questions this study aims to answer are: Is gum disease a risk factor for heart disease? Can treating gum disease lower the risk of heart disease? Adults with stable angina (a type of heart disease) and adults without heart disease may take part in this study. All participants will receive routine, non-surgical gum treatment, which is a standard dental care procedure. This includes professional cleaning to remove plaque and tartar from the teeth and practical education on tooth brushing and cleaning between the teeth. The treatment will be performed by a single researcher and completed in one visit within about one hour. Participants will: Provide a blood sample before gum treatment Receive routine, non-surgical gum treatment Return after three months for a follow-up visit Provide a second blood sample This study does not involve experimental drugs or devices. Participation is voluntary, and there is no cost to participants. The results may help researchers better understand how gum health is related to heart health.

Key facts

Study ID

NCT07412795

Run by

Ondokuz Mayıs University

People needed

60

Starts

2026-02-20

Expected to finish

2026-08-05

Last updated by the study team

2026-02-17

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Willingness to participate in the study and provide written informed consent
• Age 18 years or older
• No periodontal treatment within the past 6 months
• No use of local or systemic antibiotics within the past 3 months

You may not qualify if…

• Unwillingness to participate in the study or to provide informed consent
• Age under 18 years
• Use of local or systemic antibiotics for the treatment of widespread infection
• within the past 3 months
• Receipt of periodontal treatment within the past 6 months
• Pregnancy or lactation (for female participants)
• History of acute myocardial infarction within the past 6 months

Where it is running

• Ondokuz Mayis University — Samsun, Atakum, Turkey (Türkiye)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.