Study of DIOSHA S Lido Injection vs. YOUTHFILL Fine With Lidocaine in Treating Moderate to Severe Nasolabial Folds

Starting soon · Not applicable

Conditions studied: Nasolabial Folds, Wrinkles

In brief

Study of DIOSHA S Lido Injection vs. YOUTHFILL Fine With Lidocaine in Treating Moderate to Severe Nasolabial Folds

Key facts

Study ID

NCT07412392

Run by

Hyundae Meditech

People needed

60

Starts

2026-02-27

Expected to finish

2027-07-30

Last updated by the study team

2026-02-17

Who can join

Age: 19 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adults aged 19 to 75 years
• Voluntarily provided written informed consent
• Moderate to severe symmetrical nasolabial folds (WSRS score 3 or 4 on both sides)
• Agree to discontinue other facial dermatologic treatments (e.g., fillers, botulinum toxin, laser) during the study
• Able to understand instructions and comply with study procedures

You may not qualify if…

• Active facial skin disease, infection, or untreated scars in the treatment area
• History of severe allergy or hypersensitivity to device components
• Facial aesthetic or invasive procedures in the treatment area within 6 months prior to screening
• Use of prohibited medications within required washout periods
• Participation in another interventional clinical trial within 4 weeks prior to screening or during the study
• Pregnancy, breastfeeding, or non-compliance with contraception requirements
• Any condition deemed inappropriate by the investigator

Full record on ClinicalTrials.gov

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