Preoperative Rehabilitation for Patient With an ACL Injury
Recruiting now · Not applicable
Conditions studied: Anterior Cruciate Ligament (ACL)
In brief
Muscle qualities are critical for the recovery after an anterior cruciate ligament (ACL) injury. Before ACL reconstruction (ALCR), resistance training aims to maintain patient strength and volume in order to optimize recovery. Unanswered questions remain on the modalities of resistance training before ACLR. This protocol details a pragmatic clinical trial that primary aims to increase the maximal strength of knee extensors and flexors and to induce hypertrophy before ACLR. Participants awaiting ACLR will be recruited from outpatient rehabilitation clinics and will be randomly allocated to one group to attend a 9-weeks rehabilitation program before ACLR. Participants of 'resistance training' group will perform a training program built on the principles of strength training to increase knee muscles strength and volume. Three blocks of 3 weeks will induce a progressive increase in training load, with exercises performed close to failure. Participants of 'usual group' will perform traditional exercises including: balance/proprioceptive exercises, weight-balances exercises, and body-weight resistance training exercises. Groups will be compared on muscle strength (primary outcome), clinical outcomes (muscle volume, stiffness, knee mobility, effusion) and self-reported outcomes (quality of life, perception of knee function, pain, anxiety and depression, exertion, health consumption, participations in activities) before and after ACLR. Outcomes will be collected by a blinded assessor before and after the resistance training program (before ACLR); 4 and 9 months after the ACLR.
Key facts
- Study ID
- NCT07411625
- Run by
- Nantes University Hospital
- People needed
- 84
- Starts
- 2026-03-17
- Expected to finish
- 2027-08-15
- Last updated by the study team
- 2026-03-20
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Being over 18 years
- A first episode of an ACL injury
- An ACLR scheduled at least 10 weeks later, with a surgical technique using hamstring, gracilis, or quadriceps/patellar tendon autograft
- A minimum passive range of motion of the knee between 10° of extension deficit, and 80° of flexion
- A medical prescription for prehabilitation
- Possibility to attend prehabilitation program and post-ACLR rehabilitation in one of the 15 clinics
Where it is running
- University Hospital - Laboratoire "Motricité, Interactions, Performance" (UR 4334) — Nantes, France (enrolling)
Full record on ClinicalTrials.gov
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