Palatal Wound Healing After Free Gingival Graft Surgery

Recruiting now · Not applicable

Conditions studied: Gingival Recession, Localized, Postoperative Morbidity, Palatal Donor Site Wound Healing

In brief

This randomized controlled clinical trial aims to evaluate the effects of topical triamcinolone acetonide application on wound healing and patient-reported outcomes at the palatal donor site following free gingival graft (FGG) surgery. A total of 55 patients with mucogingival deficiencies requiring FGG will be randomly assigned to either a control group receiving a collagen membrane or a test group receiving topical triamcinolone acetonide at the donor site. All palatal donor areas will be protected with a periodontal dressing. Clinical assessments will be performed on postoperative days 3, 7, 14, and 30. Wound epithelialization will be evaluated using the hydrogen peroxide bubbling test, while wound healing and scar formation will be assessed using the Landry, Turnbull, and Howley index and the modified Manchester Scar Scale, respectively. Patient-centered outcomes, including postoperative pain, discomfort, analgesic consumption, and oral health-related quality of life, will be assessed using visual analog scales and the Oral Health Impact Profile-14 questionnaire. The findings of this study are expected to provide evidence regarding the potential benefits of topical corticosteroid use in reducing palatal donor site morbidity following FGG surgery.

Key facts

Study ID

NCT07409571

Run by

Kahramanmaras Sutcu Imam University

People needed

55

Starts

2025-10-16

Expected to finish

2026-05-20

Last updated by the study team

2026-05-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adults aged 18 years and older
• Patients presenting with insufficient attached gingiva and/or gingival recession requiring free gingival graft surgery
• Systemically healthy individuals (ASA I)
• Full-mouth plaque score (FMPS) < 15% and full-mouth bleeding score (FMBS) < 15% at the time of surgery
• Ability and willingness to provide written informed consent and comply with study procedures

You may not qualify if…

• Presence of systemic diseases that may affect wound healing (e.g., diabetes mellitus, immunological disorders)
• Use of systemic corticosteroids, immunosuppressive drugs, or anti-inflammatory medications within the last 3 months
• Current smokers or tobacco users
• Pregnancy or lactation
• History of periodontal surgery at the palatal donor site
• Presence of active infection, ulceration, or pathological lesions at the palatal donor area
• Known allergy or hypersensitivity to corticosteroids, collagen materials, or study-related medications

Where it is running

• Kahramanmaraş Sütçü İmam University — Kahramanmaraş, Kahramanmaraş, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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