A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs
Starting soon · Not applicable
Conditions studied: Substance Use, HIV Prevention
In brief
This study includes finalization of the LINKED social network intervention to improve PrEP and MOUD uptake among people who inject drugs (PWID) in collaboration with an Expert Advisory Board and staff (N=16) at The Sidewalk Project (TSP), followed by a Hybrid Type II cluster randomized trial of the LINKED intervention (versus an equal-attention control) among N=372 people who inject drugs, with 6- and 12-month follow-up assessment of PrEP and MOUD uptake. The investigators will also evaluate implementation outcomes to inform future sustainable implementation of LINKED in harm reduction organizations.
Key facts
- Study ID
- NCT07409350
- Run by
- NYU Langone Health
- People needed
- 398
- Starts
- 2027-01-01
- Expected to finish
- 2028-12-01
- Last updated by the study team
- 2026-02-13
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Aim 1 - Virtual Focus Group
- Is 18 years or older
- Is a current TSP staff
- Is capable and willing to provide consent
- Aim 2 - Intervention
- 18 years or older
- Spend majority of their time in the Los Angeles, CA area where recruited
- Able to complete surveys and group sessions in English
- Self-report to have injected drugs in the past 3 months
- Self-reported HIV negative serostatus
- Not currently on PrEP or MOUD
- Not pregnant
- If a network recruit: presents a valid recruitment coupon
- Is capable and willing to provide consent
- Aim 3 - Virtual Focus Group/Surveys
- Is 18 years or older
- Is a current TSP staff
- Is capable and willing to provide consent
You may not qualify if…
- Aims 1 and 3:
- Individuals who are not current TSP staff members will be excluded from participation.
- Aim 2:
- Under age 18;
- Does not spend majority of time in the Los Angeles, CA area where recruited;
- Unable to complete surveys and groups sessions in English;
- Does not self-report injecting drugs in past 3 months;
- Self-reported HIV positive serostatus
- Currently on PrEP or MOUD
- Currently pregnant
- If a network recruit: does not present a valid recruitment coupon
Where it is running
- University of Southern California — Los Angeles, California, United States
- The University of Chicago — Chicago, Illinois, United States
- NYU Langone Health — New York, New York, United States
Full record on ClinicalTrials.gov
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