Neurophysiology of Reward Signaling in Parkinson's Disease
Recruiting now · Not applicable
Conditions studied: Parkinson Disease
In brief
The goal of this study is to learn more about the brain activity underlying Parkinson's disease risk taking and reward seeking behaviors. The investigators will utilize neural recordings from corticostriatal structures performed during deep brain stimulation surgery to measure neural activity underlying nonmotor symptoms of Parkinson's disease.
Key facts
- Study ID
- NCT07409207
- Run by
- Vanderbilt University Medical Center
- People needed
- 75
- Starts
- 2024-09-01
- Expected to finish
- 2029-09-30
- Last updated by the study team
- 2026-06-12
Who can join
Age: 40 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center
- Planned clinical electrode trajectory that contacts caudate
- Age greater than or equal to 40
- Diagnosis of Parkinson's disease or other movement disorder
- Able to participate in intraoperative testing
- English speaking
You may not qualify if…
- Age less than 40
- Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)
Where it is running
- Vanderbilt University Medical Center — Nashville, Tennessee, United States (enrolling)
Full record on ClinicalTrials.gov
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