Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter

Recruiting now · Phase 2

Conditions studied: Joint Replacement Surgery

In brief

The purpose of this study is to determine the feasibility of administering a predetermined amount of normal saline into the intrathecal or subarachnoid space via a small spinal catheter to reduce or eliminate the effects of previously injected spinal anesthetic following lower extremity orthopedic surgery.

Key facts

Study ID

NCT07404982

Run by

Beth Israel Deaconess Medical Center

People needed

24

Starts

2026-03-19

Expected to finish

2027-12-01

Last updated by the study team

2026-07-31

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients having elective lower extremity joint replacement surgery
• Patients >18 years

You may not qualify if…

• Contraindications to spinal anesthesia (refusal, lumbar spinal hardware, spinal abnormalities)
• Patient on anticoagulation not withheld
• Patient receiving re-operation on the same joint
• Prior intra-cranial bleeding
• Patient's ASA status >3
• Non-English speaking
• Bromage score of 6 at the time of first PACU assessment post-enrollment

Where it is running

• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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