Zero CDE Technique for Lens Removal During FLACS
Starting soon · Not applicable
Conditions studied: Cataract With a Nuclear Sclerosis Grade Between 1 to 3
In brief
The Zero CDE (cumulative dissipated energy) technique facilitates cataract removal with no or minimal phaco energy. This is facilitated by a femtosecond laser, which pre-divides the cataractous lens nucleus into multiple small segments that can be aspirated without phaco energy being delivered to the eye. In the investigator's experience, this technique consistently shows a stable anterior chamber, a low complication rate, and a rapid return of vision following cataract surgery. This prospective study aims to document the outcomes with the zero CDE technique during femtosecond laser-assisted cataract surgery (FLACS).
Key facts
- Study ID
- NCT07404293
- Run by
- Bochner Eye Institute
- People needed
- 90
- Starts
- 2026-03-15
- Expected to finish
- 2027-07-14
- Last updated by the study team
- 2026-02-11
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult patients over the age of 50 years with operable cataract of nuclear sclerosis grade 1 to 3 as measured by LOCS III grading system (patients with cortical or posterior subcapsular cataract of any grade will be eligible).
- Patients must be able to provide written informed consent for participating in the study.
- Preoperative best corrected visual acuity of 20/25 or worse.
You may not qualify if…
- Patients with corneal edema, corneal guttata, pseudoexfoliation, zonular dialysis, or other ocular anomalies (e.g., inflammation, uveitis, previous trauma, suspected microbial infection, glaucoma, and macular disease).
- Patients wearing soft contact lenses will need to discontinue lens wear for 2 weeks, and hard contact lens wearers for one month prior to intraocular lens measurements.
- Women patients of childbearing potential.
- Patients undergoing arcuate keratotomy or other combined surgery with cataract.
Where it is running
- Bochner Eye Institute — Toronto, Ontario, Canada
Full record on ClinicalTrials.gov
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