Ex Vivo Cutaneous SCC

Recruiting now · Not applicable

Conditions studied: Cutaneous Squamous Cell Carcinoma

In brief

This is a prospective study including patients ( ≥ 18 years) referred for surgical treatment of primary cutaneous squamous cell carcinoma at the Department of Plastic Surgery, Rigshospitalet. After written and informed consent, patients will undergo standard surgical excision, followed by ex vivo 3D ultrasonography of the specimen using a 3Sonic device connected to a high-frequency ultrasound machine. This will create 3D ultrasound tomographic scans which will be interpreted by one investigator blinded to histopathology. The investigated outcomes will primarily be the deep margin distance. This will be compared to histopathology, where a pathologist - blinded to the ultrasonography results - will slice the entire specimen parallel to the ultrasound images. A third investigator will then match the histopathology images to the ultrasound images for correlation of the measured deep margins.

Key facts

Study ID

NCT07402616

Run by

Rigshospitalet, Denmark

People needed

30

Starts

2026-02-01

Expected to finish

2027-09-01

Last updated by the study team

2026-02-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults with primary cutaneous squamous cell carcinoma.

You may not qualify if…

• Carcinomas located on the eyelids, vulva, penis, or perianal.
• Tumors with an anticipated excision larger than 60mm.

Where it is running

• Rigshospitalet — Copenhagen, Denmark (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.