Amputations in Childhood and Neuropathic Pain
Recruiting now
Conditions studied: Pediatric, Neuropathic Pain, Phantom Limb Pain, Amputation
In brief
This observational study aims to assess the presence of neuropathic pain in children and adolescents who underwent limb amputation during childhood. The study focuses on two types of neuropathic pain: phantom limb pain and residual limb pain. It also evaluates quality of life and functional autonomy in this population and explores potential associations between neuropathic pain, autonomy, quality of life, and age at amputation. Using a mixed retrospective and prospective design, data are collected from medical records and standardized questionnaires administered during routine follow-up visits at a specialized pediatric limb anomaly center. The study seeks to improve understanding of neuropathic pain after pediatric amputation and its impact on daily functioning.
Key facts
- Study ID
- NCT07401966
- Run by
- Hopitaux de Saint-Maurice
- People needed
- 50
- Starts
- 2026-02-19
- Expected to finish
- 2027-02-02
- Last updated by the study team
- 2026-02-23
Who can join
Age: 5 and older, up to 18. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients aged between 5 and 18 years (inclusive) (Piaget's concrete operational stage to be able to complete the self-assessment questionnaires)
- Patients who underwent amputation before the age of 15 for girls and 16 for boys (average age of completion of lower limb growth)
- Patients who have not undergone surgery on the amputated limb for at least one year (to avoid bias, as any surgery involving incision can cause temporary neuropathic pain unrelated to the amputation)
- Have obtained the signature of the non-objection form by both parents/legal guardians
- Have obtained the child's consent (verbal consent but recorded)
- Be affiliated with a health insurance plan.
You may not qualify if…
- Patients who do not speak French
- Patients whose cognitive abilities are insufficient (as determined by a clinician or reported by parents) to be able to complete self-assessment questionnaires
- Patients undergoing chemotherapy (due to transient neuropathic pain)
- Patients who have received chemotherapy and whose side effects have not yet subsided (on a case-by-case basis depending on the chemotherapy used)
- Patients who have received chemotherapy causing neuropathic pain due to this treatment that has not disappeared.
- Patients placed under protective custody.
Where it is running
- Hôpitaux Paris Est Val-de-Marne - Centre de Référence des Malformations des Membres — Saint-Maurice, France (enrolling)
Full record on ClinicalTrials.gov
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