Postoperative SpO₂/FiO₂ Ratio and Analgesic Methods in Laparoscopic Surgery
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Conditions studied: Postoperative Hypoxemia
In brief
This prospective observational study aims to evaluate the association between postoperative oxygenation, assessed by the SpO₂/FiO₂ ratio, and body mass index (BMI), STOP-BANG score, and postoperative analgesic methods in patients undergoing elective laparoscopic cholecystectomy in the reverse Trendelenburg position. Postoperative SpO₂ and FiO₂ values will be recorded within the first postoperative hour, and the SpO₂/FiO₂ ratio will be calculated. Analgesic techniques applied as part of routine clinical practice will be documented. The study does not involve any additional intervention beyond standard care. The findings are expected to contribute to a better understanding of factors associated with early postoperative oxygenation and hypoxemia risk.
Key facts
- Study ID
- NCT07401589
- Run by
- Istinye University
- People needed
- 100
- Starts
- 2026-02-15
- Expected to finish
- 2026-03-31
- Last updated by the study team
- 2026-02-10
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥ 18 years
- Patients who provide written informed consent
- ASA physical status I-III
- Patients undergoing elective laparoscopic cholecystectomy
- Surgery performed in the reverse Trendelenburg position (30°)
- Expected operative duration < 3 hours
- Exclusion Criteria:
- Age < 18 years
- Refusal or inability to provide informed consent
- ASA physical status IV or higher
- Known chronic respiratory diseases (e.g., asthma, COPD)
- Severe cardiac failure (NYHA class III-IV) or advanced cardiovascular disease
- Emergency surgery
- Preoperative oxygen supplementation or baseline SpO₂ < 90%
- Prolonged intubation or perioperative respiratory complications
- Requirement for postoperative noninvasive ventilation or intensive care unit admission
- Missing SpO₂ or FiO₂ data preventing calculation of the SpO₂/FiO₂ ratio
Where it is running
- Istinye Üniversity — Istanbul, Merkez Mahallesi, Turkey (Türkiye)
Full record on ClinicalTrials.gov
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